Most of the MIDI options would be useful as keyboard shortcuts, particularly:

• Octave transpose
• Record note off (which is already a binding)
• Continue song on note
• Record velocity
• Record CCs

Obviously the numeric ones and dropdowns present more of a challenge, but at least those checkboxes would be useful since they relate to MIDI-as-step-sequencer vs. MIDI-as-recorded-performance, which is currently pretty annoying to manage if you want to switch back and forth.

A status bar message would be cool as some indication of the value of the option you just changed.

This functionality could in theory apply to other options menu checkboxes, but I don't see any that are really necessary beyond the ones that have bindings already.